It does not take the place of talking to your doctor or pharmacist. Lidocaine hydrochloride and epinephrine injection 1. Based on available data, the classification criteria are not met. Lidocaine hydrochloride was not shown to be mutagenic in the salmonellamammalian microsome test nor clastogenic in chromosome aberration assay with human lymphocytes and mouse micronucleus test. The new sds required by osha are being added daily. Dec 31, 2019 lidocaine hydrochloride, chemical name. The coefficient of variation for ten replicate analyses of samples containing 0. Bstfa can be used at full strength or with a solvent. Lidocaine hydrochloride injection, usp, 1% or 2%, contains lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management. It is not known whether this drug is excreted in human milk. Separation of lidocaine from tablet matrix components by an hplc method is provided in this application note. This compund is known to block voltagegated sodium channels in the inactivated state. No warranty, express or implied, is made and labchem inc assumes no liability resulting from the use of this sds.
Since it is a local anesthetic, contact with the eyes or skin may cause temporary. For moderately hindered or slowly reacting compounds, use bstfa with 1% or 10% tmcs catalyst. Identification of the substancemixture and of the companyundertaking. Its iupac proper chemical name is 2diethylaminon2,6dimethylphenyl acetamide. What is the recommended procedure for chemical disposal. And address 275 north field drive lake forest, illinois 60045 usa note. Lidocaine is a selective inverse peripheral histamine h1receptor agonist with an ic 50 of 32. Oct 21, 2019 lidocaine hydrochloride pharmacokinetics absorption bioavailability. The release liner is removed prior to application to the skin. The concn of lidocaine in the original samples is determined by gc analysis of an aliquot of the chloroform layer. Lidocaine also known as xylocaine or lignocaine is white ctystalline powder. Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies.
Slowly infuse lidocaine 40 mg io over 120 seconds 3. Msds examples sds sheets msds authoring services inc. Product identification product name lidocaine hydrochloride, usp product code 0082 supplier medisca inc. Lidocaine hydrochloride 2% and epinephrine msds msdsdigital. Ghs msds sds sheets for 10 normal sodium hydroxide solution in. Find msds sheets to access any material safety data sheet search our free msds online database. Page 17 safety data sheet according to 19072006ec, article 31 printing date 22. In the workplace, this material should be considered possibly irritating to the skin, eyes and respiratory tract, and a. It does not contain all the information that is known about emla. Buy nor lidocaine hydrochloride cas 7729944, a biochemical for proteomics research, from santa cruz. A topical anesthetic for the mucous membranes of the mouth and pharynx. Darby is here to help our customers and medical community navigate the ongoing outbreak of coronavirus covid19. While most healthcare practitioners will use blt cream appropriately and safely, some are not aware that its anesthetic effects are significantly greater than overthecounter numbing creams. Pr007594 pure substancemixture mixture other means of identification product code naw0021940377 recommended use of the chemical and restrictions on use recommended use personal care.
Darby dental supply, llc dental supplies, equipment, service. Lidocaine ointment fda prescribing information, side. Oeb 2 control exposure to the range of 100ugm3 to lidocaine. Lifethreatening and fatal events in infants and young children. The plasma samples were obtained at baseline, every 30 min for 3. Safety data sheet in compliance with regulation ec 19072006, regulation ec 12722008 and regulation. Formerly known as material safety data sheets, phac now refers to them as pathogen safety data sheets or psdss. These are just a few important points to remember when using blt cream. Each ml of solution for injection contains 10mg of lidocaine. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. It has a role as a local anaesthetic, an antiarrhythmia drug, an environmental contaminant, a xenobiotic and a drug allergen. Safety data sheets ruhof healthcare cleaning solutions. Faqs contact us the document library provides customers with a single pointofaccess to technical documents for our entire portfolio of instruments, assays and test kits. Lidocaine hydrochloride injection, usp intravenous for cardiac arrhythmias, is a sterile, nonpyrogenic solution prepared from lidocaine with the aid of hydrochloric acid in water for injection.
Sample globally harmonized system ghs compliant material safety data sheets. Lidocaine hydrochloride 7586 not listed not listed not listed epinephrine listed as a hazardous product in the rcra epa and. Hospira, formerly the hospital products division of abbott laboratories, was. Identification product identifier product name listerine antiseptic specification no. Lidocaine hydrochloride 2% solution msdsno 775 tuesday, july 20, 2010 to the best of our knowledge the information contained herein is accurate as of the date hereof. In the workplace, this product should be considered possibly irritating to the skin, eyes and respiratory tract. Glydo lidocaine hcl jelly, usp 2% is available in 6 ml and 11 ml singledose prefilled syringes. Lidocaine is not contraindicated in labor and delivery. We are working diligently to make sure that the products you need are available when you need them. Safety data sheet product name lidocaine hydrochloride and. Eight patients aged 2259 received 5 g of emla 5% cream applied to 25 cm2 large 2 nd degree burn areas for 30 min. Lidocaine hydrochloride injection is a solution containing lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management. Lidocaine hydrochloride and epinephrine injection is a solution containing lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management, and epinephrine, a vasoconstrictor agent.
Lidocaine is the monocarboxylic acid amide resulting from the formal condensation of n,ndiethylglycine with 2,6dimethylaniline. Buffered lidocaine hydrochloride solution with and without. Lidocaine is also an anasthetic and class ib antiarrhythmic agent. Identification of the substancemixture and of the companyundertaking product identifier xylocaine solution for oral pump spray details of the supplier of the safety data sheet. Oct 01, 2019 lidocaine is not contraindicated in labor and delivery. Identification of the substancemixture and of the companyundertaking product identifier emla cream details of the supplier of the safety data sheet. Lidocaine hydrochloride and epinephrine injection, solution hospira, inc. Hydrochloric acid may be added to adjust livers a solid onetwo punch with the unparalleled combination of two active ingredients. Firefighting measures promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. Safety data sheet for genomic dna form 050301 rev b062615 3 of 4 personal protective equipment. Should lidocaine ointment 5% be used concomitantly with other products containing lidocaine, the total dose contributed by all formulations must be kept in mind. Buy lidocaine hydrochloride monohydrate cas 6108050, a fast voltagegated sodium channel blocker, from santa cruz. Lidocaine is a synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Warning this product is not for human or veterinary use.
They are available as creams, ointments, solutions, eye drops, gels or sprays and may be applied to areas such as the skin, inside the mouth or throat, in the nose, or in the eyes. Please be aware that the website you have requested is intended for the residents of a particular country or region, as noted on that site. Your new online msds binder is a place for you to store the material safety data sheets you need. Revision date indicates the date the msds or sds was last revised.
This material could become a hazardous waste if it is mixed or otherwise comes into contact with a hazardous waste. More information about benzocaine, lidocaine, tetracaine cream. You are about to exit for another abbott country or region specific website. Page 1 of 1 msds material safety data sheet product name. Postmarketing cases of seizures, cardiopulmonary arrest, and death in patients under the age of 3 years have been reported with use of xylocaine 2% viscous solution when it. Regulatory information this product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all the information required by the controlled products regulations. Metabolites of lidocaine have been shown to be carcinogenic in laboratory animals. Oct 28, 2019 when used as a spray, or when applied by means of cotton applicators or packs, as when instilled into a cavity, the suggested dosage of lidocaine hydrochloride topical solution is 15 ml 40200 mg of lidocaine hydrochloride, i. View the certifications for endo products sold in childresistant packaging as required by the consumer product.
Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Chemical product and company information manufacturer name hospira, inc. When using, do not eat, drink or smoke and handle in accordance with good industrial hygiene and safety practices. Keep out of reach of children read label before use wash skin thoroughly after handling do not eat, drink or smoke when using this product. The unused portion should be discarded after initial use. We offer a robust portfolio of more than 7,500 products, including biosimilars, generics, brand, and overthecounter remedies. We have two ways to help you find safety data sheets. This product information should not be construed as a promotion or solicitation for any product.
If condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days, discontinue use of this product and consult with a doctor. Our msds database is an easy to use, do it yourself tool, and best of all. Possible target organs include the nervous system and cardiovascular. Identification of the substancemixture and of the companyundertaking product name. Safety data sheet for genomic dna coriell institute. Safety data sheet for genomic dna form 050301 rev b062615 4 of 4 this material, as supplied, is not a hazardous waste according to federal regulations 40 cfr 261. Commonly used as a local anaesthetic in dentistry and for minor surgery. Endo pharmaceuticals all products of endo pharmaceuticals. If eye irritation persists, get medical adviceattention.
Safety data sheet according to 29cfr19101200 and ghs rev. Download msds sheet pdf download package insert pdf. Chemical product and company identification manufacturer name and address lake forest, illinois 60045 hospira, inc. Topical anesthetics are medicines that numb and reduce the sensation of pain in the area to which they are applied. Lidoderm lidocaine patch 5% is comprised of an adhesive material containing 5% lidocaine, which is applied to a nonwoven polyester felt backing and covered with a polyethylene terephthalate pet film release liner. Buy lidocaine hydrochloride cas 73789, an antiarrhythmic compound, from santa cruz. This tool can help you determine the maximum dose for each type of local anesthetic sold in the u. Generic development of topical dermatologic products. Including safety glasses or goggles, gloves, and appropriate clothing to prevent skin exposure. This includes a discussion on the implementation of quality by design concepts during development to ensure the generic drug product has similar desired quality attributes to. Local anesthetic cream prepared from lidocainetetracaine. The release liner is removed prior to application to. Enzymatic detergents, contamination monitoring, steris, medivators, ecolab, endoscope reprocessing, enzyme detergents, patient safety, scope cleaning, ercp, hai.
Msds sds are dated when they are originally issued and when any significant change has been made to the chemical compound or research has revealed a health or physical hazard different from what was originally stated. Lidocaine in gel knowledge base by microsolv technology. Identification of the substancemixture and the companyundertaking product identifier material name. Local anesthetic cream prepared from lidocainetetracaine eutectic mixture keiichi ohzeki,a masaki kitahara,b noriko suzuki,c. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltagegated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. In most applications it is advisable to use an excess of the silylating reagent at least a 2. Lidocaine hydrochloride and epinephrine injection page 6 of 6 section 15. Mylan is a global healthcare company focused on making high quality medicines available to everyone who needs them. Diagnostics safety data sheets sds united states and international. The systemic concentrations for both lidocaine and tetracaine in all the samples were below the lower limits of quantification for the assays used lidocaine 100 ngml, tetracaine 5. To see more msds documents from our industryleading safety data sheet sds database use our msds search tool. Prime extension set with lidocaine note that the priming volume of the ezconnect extension set is approximately 1. Lidocaine hydrochloride monohydrate cas 6108050 scbt.
Studies in animals have not shown that lidocaine causes adverse effects on the fetus. In contrast, the epinephrinefree solutions retained at least 94. Oraqix has a gel consistency that ensures localized absorption on the desired treatment area. Absorbed from the gi tract, but passes into hepatic circulation and only about 35% of an oral dose reaches the systemic circulation unchanged. Lidocaine hydrochloride monograph for professionals. Venous blood samples drawn at set intervals up to 120 min after cream. Blt cream benzocaine lidocaine tetracaine topical anesthetic. Environmental protection agency epa or state authority, is waste that presents a danger to human health andor the environment. If swallowed, get medical help or contatct a poison control center right away. Information in this sds is from available published sources and is believed to be accurate. Lidocaine investigated as a drug, mutagen, primary irritant, and reproductive effector. Immediately call a poison center or medical professional. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only.
Glydo lidocaine hcl jelly, usp 2% also contains hypromellose, and the resulting mixture maximizes contact with mucosa and provides lubrication for instrumentation. Nor lidocaine hydrochloride cas 7729944 scbt santa. No action shall be taken involving any personal risk or without suitable. Gentamicin a broad spectrum antibiotic with not less than 500 mcg. Original article emla anaesthetic cream for debridement of. Your new online msds binder is a place for you to store the material safety data sheets you need to. Dailymed lidocaine lidocaine hydrochloride injection, solution. Sigmaaldrich offers a number of lidocaine products.1257 1177 338 1238 211 1240 864 996 1485 208 1099 1303 335 1246 1037 142 1000 1195 1502 746 277 1095 1107 1053 32 586 153 14 939 483 510 56 568 1484 1344 563 1367